Description

4-Chloro-2-Fluoroaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated and chlorinated aromatic systems.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms enhance biological activity and stability.
• Dye and Pigment Manufacturing: Serves as a starting material for producing specialized azo dyes and organic pigments.
• Material Science Research: Employed in the development of liquid crystals, organic semiconductors, and other advanced functional materials.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for creating complex biaryl structures.

Basic Information

Product Name	4-Chloro-2-Fluoroaniline
CAS No.	57946-56-2
Molecular Formula	C6H5ClFN
Molecular Weight	145.56 g/mol
Synonyms	2-Fluoro-4-chloroaniline; 4-Chloro-2-fluoro-benzenamine; 1-Amino-4-chloro-2-fluorobenzene; Benzenamine, 4-chloro-2-fluoro-; 4-Chloro-2-fluorophenylamine; 2-Fluoro-4-chlorophenylamine; 4-Chloro-2-fluoroaniline (primary name)
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoroaniline is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay, impurity profiling, and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting purity, physical characteristics, and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	30 - 34 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.