Description

Hydroxyaldol-Histidine is a specialized amino acid derivative that combines the structural features of histidine with an aldol moiety. This unique molecular architecture makes it a valuable chiral building block and intermediate for advanced chemical synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel compounds, including potential active pharmaceutical ingredients (APIs) and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for targeted therapies.
• Biochemical Research: Used in enzymatic studies and as a precursor for synthesizing modified peptides and histidine analogs to investigate protein function.
• Fine Chemical Synthesis: Acts as a building block for creating complex, high-value organic molecules with specific stereochemical configurations.
• Cosmetic Ingredient Development: Explored for use in synthesizing novel, bioactive compounds for advanced skincare formulations.
• Agrochemical Research: Investigated as an intermediate for developing new, more selective crop protection agents.

Basic Information

Product Name	Hydroxyaldol-Histidine
CAS No.	57944-40-8
Molecular Formula	C9H14N3O4
Molecular Weight	228.23 g/mol
Synonyms	L-Histidine, 2-[(1-hydroxy-2-oxo-2-phenylethyl)amino]-; (2S)-2-[[(2R)-1-Hydroxy-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)propanoic acid; Hydroxyaldol-L-histidine; Histidine hydroxyaldol derivative; 2-[(1-Hydroxy-2-oxo-2-phenylethyl)amino]-3-(1H-imidazol-4-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our Hydroxyaldol-Histidine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.