Description

Thymine Bromohydrin is a halogenated derivative of the nucleobase thymine, serving as a key synthetic intermediate in organic and medicinal chemistry. Its value lies in providing a reactive bromohydrin moiety for selective functionalization and ring-forming reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, as well as in academic settings for studying nucleic acid chemistry and modification.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Agrochemical Research: Used in developing new active ingredients for crop protection products.
• Nucleic Acid Chemistry: Serves as a modified nucleobase precursor for oligonucleotide synthesis and biochemical probes.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, particularly in halogenation and cyclization reactions.
• Chemical Biology: Employed in the creation of labeled or cross-linking agents for studying biomolecular interactions.

Basic Information

Product Name	Thymine Bromohydrin
CAS No.	57908-04-0
Molecular Formula	C5H7BrN2O3
Molecular Weight	223.03 g/mol
Synonyms	5-Bromomethyl-6-hydroxy-5,6-dihydrothymine; 5-(Bromomethyl)-5,6-dihydro-6-hydroxythymine; 5-Bromomethyl-5,6-dihydro-6-hydroxythymine; 1,3-Dihydro-5-(bromomethyl)-6-hydroxy-5-methyl-2,4(1H,3H)-pyrimidinedione; Thymine, 5-(bromomethyl)-5,6-dihydro-6-hydroxy-; Bromohydrin of thymine
EINECS	Contact for details

Quality Control

Our Thymine Bromohydrin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.