Description

Pyro(α-Aminoadipyl)-Histidyl-Prolinamide is a specialized peptide derivative of significant interest in advanced biochemical research and development. This compound serves as a key intermediate and reference standard in the synthesis and study of more complex peptide structures and their biological activities. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry, medicinal chemistry, and proteomics. The product is supplied to meet the stringent purity requirements of these high-value applications.

Application

• Pharmaceutical Research & Development: As a crucial building block or intermediate in the synthesis of novel therapeutic peptides and peptidomimetics.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to understand and optimize peptide-based drug candidates.
• Biochemical Research: Serves as a reference standard or substrate in enzymatic studies and metabolic pathway analysis.
• Proteomics & Peptide Library Synthesis: Employed in the construction of diverse peptide libraries for screening against biological targets.
• Academic Research: Utilized in university and institutional labs for fundamental studies in peptide science and chemical biology.
• Contract Research Organizations (CROs): Supplied to CROs supporting drug discovery programs for client pharmaceutical and biotech firms.

Basic Information

Product Name	Pyro(α-Aminoadipyl)-Histidyl-Prolinamide
CAS No.	57884-93-2
Molecular Formula	C22H32N6O6
Molecular Weight	476.53 g/mol
Synonyms	Pyroglutamyl-α-aminoadipyl-histidyl-prolinamide; L-α-Aminoadipyl-L-histidyl-D-proline Amide, 1-Pyroglutamyl Derivative; (S)-2-((S)-6-Amino-2-((S)-1-(2-amino-2-oxoethyl)-2-imidazol-4-yl)ethylamino)-1-carboxyhexanoyl)pyrrolidine-2-carboxamide; Cyclo(L-α-aminoadipyl-L-histidyl-D-prolinamide); A potential precursor in β-lactam biosynthesis research.
EINECS	Contact for details

Quality Control

Our Pyro(α-Aminoadipyl)-Histidyl-Prolinamide is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.