Description

4-Bromo-2-Fluorobenzaldehyde is a versatile halogenated benzaldehyde derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine atoms on the aromatic ring, which allows for selective functionalization and the introduction of complexity into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating specialized chemical libraries.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	4-Bromo-2-Fluorobenzaldehyde
CAS No.	57848-46-1
Molecular Formula	C7H4BrFO
Molecular Weight	203.01 g/mol
Synonyms	2-Fluoro-4-bromobenzaldehyde; 4-Bromo-2-fluorobenzenecarboxaldehyde; 4-Bromo-2-fluorobenzaldehyde; 57848-46-1; p-Bromo-o-fluorobenzaldehyde; Benzenecarboxaldehyde, 4-bromo-2-fluoro-; 4-Bromo-2-fluoro-benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorobenzaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, assay, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.