Description

(5-Iodo-2,4-Dioxo-3,4-Dihydro-2H-Pyrimidin-1-Yl)-Acetic Acid CAS NO 57846-83-0 is a high-purity iodinated uracil derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and nucleoside analogs. It is primarily needed by research institutions and pharmaceutical manufacturers focused on antiviral, anticancer, and diagnostic agent development.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used in the study of enzyme mechanisms, DNA/RNA interactions, and as a probe in molecular biology.
• Diagnostic Agent Development: Serves as a precursor for radioiodinated compounds used in medical imaging and diagnostics.
• Agrochemical Research: Intermediate in the development of new generation pesticides and plant growth regulators.
• Material Science: Potential monomer or additive for creating specialized polymers with unique electronic or biological properties.

Basic Information

Product Name	(5-Iodo-2,4-Dioxo-3,4-Dihydro-2H-Pyrimidin-1-Yl)-Acetic Acid
CAS No.	57846-83-0
Molecular Formula	C6H5IN2O4
Molecular Weight	296.02 g/mol
Synonyms	1-Carboxymethyl-5-iodouracil; 5-Iodo-1-carboxymethyluracil; (5-Iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid; 5-Iodoorotic acid derivative; N-Carboxymethyl-5-iodouracil; 5-Iodo-N-(carboxymethyl)uracil; 1-Acetic acid-5-iodouracil
EINECS	Contact for details

Quality Control

Our (5-Iodo-2,4-Dioxo-3,4-Dihydro-2H-Pyrimidin-1-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.