Description

2-(Trifluoromethylthio)Benzaldehyde is a versatile fluorinated aromatic aldehyde building block, distinguished by its trifluoromethylthio (-SCF₃) substituent. This compound is valued for its role in introducing the highly lipophilic and electron-withdrawing SCF₃ group into target molecules, which can significantly alter their physicochemical and biological properties. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for developing new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the SCF₃ group can enhance metabolic stability and bioactivity.
• Material Science Research: Serves as a precursor for synthesizing specialized ligands, catalysts, and monomers for advanced polymeric materials.
• Organic Synthesis Building Block: Employed in various name reactions (e.g., condensations, nucleophilic additions) to create complex, fluorinated molecules for research purposes.
• Liquid Crystal & Electronic Chemicals: Potential use in the development of fluorinated components for electronic displays and organic semiconductors.

Basic Information

Product Name	2-(Trifluoromethylthio)Benzaldehyde
CAS No.	57830-48-5
Molecular Formula	C₈H₅F₃OS
Molecular Weight	206.18 g/mol
Synonyms	2-[(Trifluoromethyl)thio]benzaldehyde; o-(Trifluoromethylthio)benzaldehyde; Benzaldehyde, 2-[(trifluoromethyl)thio]-; 2-(Trifluoromethylsulfanyl)benzaldehyde; α,α,α-Trifluoro-o-thiocresol aldehyde; 2-SCF₃-Benzaldehyde
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, it is recommended to keep under an inert atmosphere (e.g., nitrogen or argon). Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.