Description

Des-Gly10,[D-Phe6]-Lh-Rh Ethylamide is a synthetic peptide analog of luteinizing hormone-releasing hormone (LHRH). This compound is significant for its potent biological activity and high receptor binding affinity, making it a critical tool in advanced endocrinology and pharmaceutical research. It is primarily needed by research institutions and pharmaceutical developers focused on neuroendocrinology, reproductive biology, and the development of novel therapeutic agents.

Application

• Biomedical Research: Used as a high-potency agonist in studies of the hypothalamic-pituitary-gonadal axis and receptor signaling pathways.
• Pharmaceutical Development: Serves as a key reference standard or active pharmaceutical ingredient (API) in the preclinical development of hormone-related therapies.
• Endocrinology Studies: Essential for investigating the physiological and pathological roles of LHRH and its analogs in laboratory settings.
• Receptor Binding Assays: Employed in competitive binding experiments to characterize LHRH receptor subtypes and affinity.
• Biochemical Tool: Utilized to stimulate gonadotropin secretion in controlled *in vitro* cell culture models.
• Peptide Chemistry Reference: Acts as a model compound for studying structure-activity relationships (SAR) in peptide analog design.

Basic Information

Product Name	Des-Gly10,[D-Phe6]-Lh-Rh Ethylamide
CAS No.	57773-64-5
Molecular Formula	C₆₄H₈₃N₁₇O₁₂
Molecular Weight	1266.5 g/mol
Synonyms	Des-Gly10,[D-Phe6]-LHRH Ethylamide; [D-Phe6, Des-Gly10]-LHRH Ethylamide; Luteinizing Hormone-Releasing Hormone (6-D-Phenylalanine, 10-desglycine) Ethylamide; LHRH Agonist ([D-Phe6, Des-Gly-NH₂¹⁰]); GnRH Agonist Analog; P-Glu-His-Trp-Ser-Tyr-D-Phe-Leu-Arg-Pro-NHEt; Fertirelin Acetate Related Compound
EINECS	Contact for details

Quality Control

Our Des-Gly10,[D-Phe6]-Lh-Rh Ethylamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.