Description

Glutamic Acid, 2-Hydroxy- is a specialized amino acid derivative, also known as 2-Hydroxyglutamic acid, with the CAS registry number 57772-70-0. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in protease inhibitor and neurological agent synthesis.
• Biochemical Research: Used as a standard or reagent in enzymatic studies, metabolic pathway analysis, and as a precursor for more complex biochemical probes.
• Agrochemical Synthesis: Employed in the development of advanced, targeted herbicides and plant growth regulators that require specific stereochemistry.
• Peptide Chemistry: Serves as a modified amino acid residue for incorporating unique structural and functional properties into synthetic peptides and peptidomimetics.
• Fine Chemical Production: Acts as a versatile intermediate for the synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Cosmetic Ingredient Synthesis: Potential precursor for the development of novel, skin-compatible active ingredients and moisturizing agents.

Basic Information

Product Name	Glutamic Acid, 2-Hydroxy-
CAS No.	57772-70-0
Molecular Formula	C5H9NO5
Molecular Weight	163.13 g/mol
Synonyms	2-Hydroxyglutamic Acid; (2S)-2-Amino-2-hydroxy-pentanedioic Acid; L-2-Hydroxyglutamic Acid; 2-Hydroxy-DL-glutamic Acid; α-Hydroxyglutamic Acid; 2-Amino-2-hydroxyglutaric Acid; Hydroxyglutamate; 2-HGA
EINECS	Contact for details

Quality Control

Our Glutamic Acid, 2-Hydroxy- is produced under strict quality management protocols. We offer material suitable for research and industrial synthesis, with typical purity levels exceeding 95% (HPLC). Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity (where applicable), and impurity profiles. Specifications can be tailored to meet specific project requirements, including higher purity grades for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent absorption of atmospheric moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation (where applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.