Description

Oxytocin, His(4)- CAS NO 57735-87-2 is a synthetic analogue of the neuropeptide hormone oxytocin, modified with a histidine tag. This high-purity peptide is critical for advanced biochemical research and pharmaceutical development, offering a standardized tool for studying receptor binding, signal transduction, and neuroendocrine functions. It is primarily utilized by research institutions, diagnostic kit manufacturers, and biopharmaceutical companies engaged in neuroscience, endocrinology, and therapeutic peptide discovery.

Application

• Biochemical Research: A key reagent for studying oxytocin receptor (OXTR) interactions, signaling pathways, and cellular responses in neurological and endocrine systems.
• Pharmaceutical Development: Serves as a reference standard or an intermediate in the R&D of novel peptide-based therapeutics targeting social behavior, stress, and reproductive health.
• Diagnostic Assays: Used as a calibrated antigen or standard in the development and validation of immunoassays (ELISA, RIA) for oxytocin level quantification.
• Neuroscience Studies: Essential for in vitro and in vivo investigations into the role of oxytocin in social bonding, anxiety, memory, and maternal behavior.
• Academic & Institutional Research: Provides a reliable, high-quality compound for university labs and research centers conducting fundamental peptide hormone research.
• Bioconjugation & Probe Synthesis: The histidine tag facilitates purification and enables conjugation with fluorophores or other labels for imaging and detection studies.

Basic Information

Product Name	Oxytocin, His(4)- CAS NO 57735-87-2
CAS No.	57735-87-2
Molecular Formula	C48H68N14O12S2
Molecular Weight	1081.3 g/mol
Synonyms	Histidine-tagged Oxytocin; [His4]-Oxytocin; Oxytocin (4-His); 1-{6-Amino-2-[(4-{[(2-amino-2-oxoethyl)amino]carbonyl}butyl)amino]-1-(1H-imidazol-4-ylmethyl)-5-oxohexyl}-L-prolyl-L-leucylglycinamide; Oxytocin analogue; Tagged Oxytocin peptide
EINECS	Contact for details

Quality Control

Our Oxytocin, His(4)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation, ensuring it meets stringent specifications for research use. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.