Description

Poly-ε-Cbz-D-Lysine Mol. Wt.*250,000-500,000 is a synthetic, high-molecular-weight polymer derived from the protected amino acid derivative, ε-Carbobenzoxy-D-lysine. This material is a critical advanced intermediate for the development of specialized biomaterials, offering controlled molecular architecture and functional group presentation. It is primarily utilized by research institutions and industrial R&D departments focused on drug delivery systems, biodegradable polymers, and tissue engineering scaffolds.

Application

• Biomedical Research: As a key building block for synthesizing novel, biodegradable polymers with tailored degradation rates and mechanical properties.
• Drug Delivery Systems: For the fabrication of controlled-release carriers, such as microspheres or nanoparticles, where the Cbz protecting group allows for subsequent functionalization.
• Tissue Engineering: In the development of three-dimensional scaffolds that support cell adhesion and growth, leveraging its polypeptide-like structure.
• Polymer Chemistry Studies: As a model compound for investigating polymerization kinetics, chain conformation, and the properties of poly(amino acid)s.
• Surface Modification: For coating medical devices or implants to improve biocompatibility and reduce immune response.
• Conjugate Chemistry: Serving as a polymeric backbone for attaching therapeutic agents, targeting ligands, or imaging probes.

Basic Information

Product Name	Poly-ε-Cbz-D-Lysine Mol. Wt.*250,000-500,000
CAS No.	57705-97-2
Molecular Formula	(C14H18N2O4)n
Molecular Weight	250,000 - 500,000 (Average Molecular Weight)
Synonyms	Poly(Nε-carbobenzoxy-D-lysine); Poly(Cbz-D-Lys); Poly(Nε-Cbz-D-lysine); Poly(ε-Cbz-D-lysine); Poly(Nε-benzyloxycarbonyl-D-lysine); Poly(D-Lys(Z)); Poly(ε-benzyloxycarbonyl-D-lysine); Poly(Nε-Z-D-lysine)
EINECS	Contact for details

Quality Control

Our Poly-ε-Cbz-D-Lysine is produced under controlled conditions to ensure batch-to-batch consistency. Each lot undergoes rigorous quality testing, including analysis of molecular weight distribution, purity, and residual monomer content. A comprehensive Certificate of Analysis (COA) detailing specifications and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Average Molecular Weight (GPC)	250,000 - 500,000 Da
Polydispersity Index (PDI)	< 2.0
Assay (HPLC)	> 95% (Polymer Content)
Residual Solvent (GC)	Meets ICH guidelines
Loss on Drying	< 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.