Description

3-(4-Pyrimidin-2-Ylpiperazin-1-Yl)Propan-1-Amine is a high-purity, functionalized piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by pharmaceutical R&D teams and custom synthesis specialists focused on creating new therapeutic agents, particularly in central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological receptors and enzymes.
• Chemical Biology Research: Used as a molecular scaffold or linker in the design of probes and tool compounds for studying biological pathways.
• Agrochemical Development: Serves as a building block for creating new active ingredients in crop protection research.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs for the production of complex, high-value molecules for clinical trials.
• Ligand Synthesis for Catalysis: Can be utilized to create specialized ligands for metal-catalyzed reactions in fine chemical production.
• Academic & Institutional Research: Used in universities and research institutes for methodological development and discovery chemistry projects.

Basic Information

Item	Details
Product Name	3-(4-Pyrimidin-2-Ylpiperazin-1-Yl)Propan-1-Amine
CAS No.	57648-83-6
Molecular Formula	C11H19N5
Molecular Weight	221.31 g/mol
Synonyms	1-(3-Aminopropyl)-4-(pyrimidin-2-yl)piperazine; 2-[4-(3-Aminopropyl)piperazin-1-yl]pyrimidine; 3-(4-Pyrimidin-2-ylpiperazin-1-yl)propylamine; N-(3-Aminopropyl)-N'-(2-pyrimidinyl)piperazine; 57648-83-6; 3-(4-(Pyrimidin-2-yl)piperazin-1-yl)propan-1-amine
EINECS	Contact for details

Quality Control

Our 3-(4-Pyrimidin-2-Ylpiperazin-1-Yl)Propan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.