Description

2-(2,2,2-Trifluoro-Ethyl)-Phenylamine is a specialized aromatic amine building block featuring a trifluoroethyl substituent, which imparts unique electronic and steric properties. This compound is valued for its role as a key intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the trifluoromethyl group is crucial for modulating biological activity and material stability. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and organic electronic materials with specific dielectric properties.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and creating complex molecular architectures in medicinal and synthetic chemistry.
• Fluorinated Compound Library: A valuable reagent for constructing libraries of fluorinated compounds for high-throughput screening in drug discovery programs.

Basic Information

Product Name	2-(2,2,2-Trifluoro-Ethyl)-Phenylamine
CAS No.	57631-04-6
Molecular Formula	C8H8F3N
Molecular Weight	175.15 g/mol
Synonyms	2-(2,2,2-Trifluoroethyl)aniline; 2-(Trifluoroethyl)aniline; 1-Amino-2-(2,2,2-trifluoroethyl)benzene; α,α,α-Trifluoro-o-toluidine; Benzenamine, 2-(2,2,2-trifluoroethyl)-; 2-(Trifluoroethyl)phenylamine; o-(Trifluoroethyl)aniline; 2-Aminobenzyl trifluoride
EINECS	Contact for details

Quality Control

Every batch of 2-(2,2,2-Trifluoro-Ethyl)-Phenylamine is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards, and comprehensive analytical testing is performed using advanced techniques such as GC, HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.