Description

m-Fluorophenyl Trifluoromethanesulfonate is a high-purity, reactive aryl triflate ester used as a versatile building block in advanced organic synthesis. Its value lies in its ability to act as a superior leaving group in cross-coupling reactions, enabling the efficient construction of complex fluorinated aromatic systems. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key reagent in Suzuki-Miyaura, Stille, and Negishi cross-coupling reactions for creating biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used to introduce the meta-fluorophenyl moiety into novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized fluorinated ligands for metal catalysis.
• Materials Science Research: Building block for creating fluorinated monomers and polymers with tailored properties for electronic or optical applications.
• Chemical Biology Probes: Utilized in the synthesis of fluorinated analogs of biomolecules for metabolic and binding studies.
• Scale-up Process Chemistry: Employed in route development and optimization for the commercial manufacturing of fluorinated compounds.

Basic Information

Product Name	m-Fluorophenyl Trifluoromethanesulfonate
CAS No.	57606-65-2
Molecular Formula	C7H4F4O3S
Molecular Weight	244.16 g/mol
Synonyms	3-Fluorophenyl Trifluoromethanesulfonate; 3-Fluorophenyl Triflate; m-Fluorophenyl Triflate; Trifluoromethanesulfonic Acid 3-Fluorophenyl Ester; 1-Fluoro-3-(trifluoromethanesulfonyloxy)benzene; 3-Fluoro-1-(trifluoromethanesulfonyloxy)benzene; (3-Fluorophenyl) Triflate
EINECS	Contact for details

Quality Control

Every batch of m-Fluorophenyl Trifluoromethanesulfonate is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure it meets the exacting standards required for research and process chemistry. Our quality systems are designed to guarantee batch-to-batch consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture ingress and decomposition. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.