Description

2'-Fluorobiphenyl-4-Carbaldehyde is a high-purity fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. Its unique structure, featuring both a biphenyl core and a reactive formyl group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances bioavailability and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials in display and lighting technologies.
• Ligand & Catalyst Development: Employed to create sophisticated chiral ligands and organocatalysts for asymmetric synthesis.
• Polymer & Resin Modification: Incorporated into polymer backbones to alter thermal stability, solubility, and optical properties of high-performance materials.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and constructing complex molecular architectures in academic and industrial labs.

Basic Information

Item	Detail
Product Name	2'-Fluorobiphenyl-4-Carbaldehyde
CAS No.	57592-42-4
Molecular Formula	C₁₃H₉FO
Molecular Weight	200.21 g/mol
Synonyms	4-Formyl-2'-fluorobiphenyl; 2'-Fluoro-4-biphenylcarboxaldehyde; (2'-Fluoro[1,1'-biphenyl]-4-yl)methanal; 2-Fluorobiphenyl-4-carboxaldehyde; 4-Biphenylcarboxaldehyde, 2'-fluoro-; 2'-Fluoro-4-formylbiphenyl; 2-Fluoro-4'-formylbiphenyl
EINECS	Contact for details

Quality Control

Every batch of 2'-Fluorobiphenyl-4-Carbaldehyde is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.