Description

Lhrh, Phe(6)- CAS NO 57521-78-5 is a synthetic peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH), specifically modified at the sixth position with a phenylalanine derivative. This compound is a critical intermediate and research tool in the development of advanced peptide-based therapeutics and diagnostic agents. It is primarily utilized by pharmaceutical R&D departments, biotechnology firms, and academic research institutions focused on endocrinology, oncology, and reproductive medicine.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel LHRH agonist and antagonist analogs for therapeutic applications.
• Oncology Studies: Used in preclinical research for developing targeted therapies for hormone-dependent cancers, such as prostate and breast cancer.
• Endocrinology Research: A vital tool for studying the hypothalamic-pituitary-gonadal axis, receptor binding, and signal transduction mechanisms.
• Peptide Chemistry & Process Development: Employed in method development for solid-phase peptide synthesis (SPPS), purification, and analytical characterization.
• Reference Standard: Acts as a high-purity chemical reference standard for quality control and analytical method validation in GMP/GLP environments.
• Veterinary Pharmaceutical Development: Investigated for applications in animal health, particularly in fertility control and reproductive management.

Basic Information

Item	Details
Product Name	Lhrh, Phe(6)- CAS NO 57521-78-5
CAS No.	57521-78-5
Molecular Formula	C64H83N17O13
Molecular Weight	1282.5 g/mol
Synonyms	LHRH (6-D-Phenylalanine); [D-Phe6]-LHRH; Gonadorelin (6-D-Phenylalanine) analog; Luteinizing Hormone-Releasing Hormone, [D-Phe6]-; pGlu-His-Trp-Ser-Tyr-D-Phe-Leu-Arg-Pro-Gly-NH2; D-Phe6-LHRH; LH-RH, [D-Phe6]-; Fertirelin acetate related peptide
EINECS	Contact for details

Quality Control

Our Lhrh, Phe(6)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. For long-term storage, keep desiccated under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (IC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.