Description

H-Asn-NH2 HCl is a protected derivative of the amino acid L-asparagine, specifically its amide, presented as a hydrochloride salt for enhanced stability and handling. This high-purity building block is critical for advanced peptide synthesis and pharmaceutical research, where precise molecular control is paramount. It serves as an essential intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing novel therapeutic peptides and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key protected amino acid derivative in the solid-phase and solution-phase synthesis of complex peptide-based drugs and APIs.
• Biochemical Research: Used as a specialized reagent in proteomics research, enzyme substrate studies, and metabolic pathway investigations.
• Peptide Library Construction: Essential for combinatorial chemistry and the development of diverse peptide libraries for drug discovery and screening.
• Fine Chemical Synthesis: Serves as a chiral building block for the synthesis of non-peptide molecules with specific biological activities.
• Agrochemical Research: Potential intermediate in the development of novel, biologically active crop protection agents.

Basic Information

Item	Detail
Product Name	H-Asn-NH2 HCl
CAS No.	57471-69-9
Molecular Formula	C4H10N3O2 • HCl
Molecular Weight	183.60 g/mol
Synonyms	L-Asparaginamide hydrochloride; H-Asn-NH2•HCl; Asparagine amide hydrochloride; 2-Amino-3-carbamoylpropanoic acid amide hydrochloride; (S)-2-Amino-3-carbamoylpropanamide hydrochloride; Asn-NH2 HCl; Protected L-Asparagine amide
EINECS	Contact for details

Quality Control

Our H-Asn-NH2 HCl is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines, and our quality systems support compliance with global regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.