Description

Premazepam is a benzodiazepine derivative with the CAS registry number 57435-86-6, recognized for its specific pharmacological profile. This compound is of significant interest in advanced pharmaceutical research and development, particularly in the study of central nervous system (CNS) activity. It serves as a critical intermediate or reference standard for researchers and manufacturers in the pharmaceutical and life sciences sectors.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of novel benzodiazepine-based therapeutic agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Biochemical Research: Employed in preclinical studies to investigate GABAA receptor modulation and related neurological pathways.
• Active Pharmaceutical Ingredient (API) Development: A key starting material in the development pipeline for potential CNS-targeting medications.

Basic Information

Product Name	Premazepam
CAS No.	57435-86-6
Molecular Formula	C19H17ClN2O2
Molecular Weight	340.80 g/mol
Synonyms	7-Chloro-1-(cyclopropylmethyl)-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Chloro-1-(cyclopropylmethyl)-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one; Premazepamum; LS-519; CB-8025
EINECS	Contact for details

Quality Control

Our Premazepam is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-grade specifications for research use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.