Description

1,3-Dimethyl-5-Isopropyl-5-(Oxiranylmethyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized heterocyclic compound featuring a pyrimidinetrione core functionalized with an oxiranylmethyl (epoxide) group. This unique molecular structure makes it a valuable high-purity intermediate for advanced organic synthesis, particularly in the development of pharmaceuticals and fine chemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), leveraging its reactive epoxide moiety for ring-opening reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators where the pyrimidinetrione scaffold is biologically active.
• Fine Chemical Synthesis: Serves as a precursor for creating complex molecules used in dyes, pigments, and advanced material science applications.
• Cross-linking Agent: Potential use in polymer chemistry, where the epoxide group can participate in curing reactions to form thermosetting resins.
• Bioconjugation Chemistry: The epoxide functionality can be utilized for modifying proteins, peptides, or other biomolecules under mild conditions.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	1,3-Dimethyl-5-Isopropyl-5-(Oxiranylmethyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	57397-01-0
Molecular Formula	C12H18N2O4
Molecular Weight	254.28 g/mol
Synonyms	5-(Oxiranylmethyl)-5-isopropyl-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione; 5-Isopropyl-5-(oxiranylmethyl)-1,3-dimethylbarbituric Acid; 1,3-Dimethyl-5-(1-methylethyl)-5-(oxiranylmethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; Epoxypropyl Isopropyl Dimethyl Barbiturate; Glycidyl Isopropyl Dimethyl Barbiturate; 57397-01-0; 5-(2,3-Epoxypropyl)-5-isopropyl-1,3-dimethylbarbituric Acid
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-5-Isopropyl-5-(Oxiranylmethyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, impurity profile, and physical characteristics. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.