Description

5-(3-Chloro-2-Hydroxypropyl)-1,3-Dimethyl-5-Phenyl-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized heterocyclic organic compound belonging to the barbiturate derivative class. This chemical is valued for its role as a key synthetic intermediate in the production of high-value pharmaceuticals and advanced organic materials. It is primarily sought by research and development laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and other complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of barbiturate-based active pharmaceutical ingredients (APIs) and other therapeutic agents.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic frameworks and exploring new chemical entities.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, dyes, and performance materials.
• Biochemical Research: Potential use in studies involving central nervous system (CNS) activity due to its structural relationship to barbiturates.
• Agrochemical Development: Investigated as an intermediate for creating novel crop protection agents and pesticides.
• Material Science: Exploration of its use in polymer modification and as a component in advanced organic electronic materials.

Basic Information

Product Name	5-(3-Chloro-2-Hydroxypropyl)-1,3-Dimethyl-5-Phenyl-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	57396-64-2
Molecular Formula	C₁₅H₁₇ClN₂O₄
Molecular Weight	324.76 g/mol
Synonyms	1,3-Dimethyl-5-phenyl-5-(3-chloro-2-hydroxypropyl)barbituric acid; 5-(3-Chloro-2-hydroxypropyl)-1,3-dimethyl-5-phenylbarbituric acid; 1,3-Dimethyl-5-phenyl-5-(3-chloro-2-hydroxypropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Phenyl-5-(3-chloro-2-hydroxypropyl)-1,3-dimethylbarbituric acid; Chlorohydroxypropylphenyldimethylbarbituric Acid; NSC 113928
EINECS	Contact for details

Quality Control

Our 5-(3-Chloro-2-Hydroxypropyl)-1,3-Dimethyl-5-Phenyl-2,4,6(1H,3H,5H)-Pyrimidinetrione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for pharmaceutical and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.