Description

Alanine, n-Formyl-2-Mercapto- (9Ci) is a specialized, high-purity derivative of alanine featuring both formyl and mercapto functional groups, making it a valuable building block for advanced chemical synthesis. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds for developing novel pharmaceuticals, peptide mimetics, and biochemical probes. It is primarily utilized in the pharmaceutical R&D sector for drug discovery and in fine chemical production for creating complex, sulfur-containing target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting cysteine protease enzymes or requiring thiol-based bioisosteres.
• Peptide Chemistry & Modification: Used for the site-specific introduction of protected thiol and formyl groups into peptide chains, enabling advanced conjugation strategies and structural studies.
• Bioconjugation & Probe Development: Acts as a versatile linker or functional handle for creating fluorescent probes, antibody-drug conjugates (ADCs), and other bioconjugates due to its reactive thiol moiety.
• Chemical Biology Research: Employed in studying enzyme mechanisms, protein interactions, and redox biology as a tool compound or a substrate analog.
• Fine Chemical Synthesis: Utilized as a chiral building block for the asymmetric synthesis of complex organic molecules and natural product analogs in research and development.

Basic Information

Product Name	Alanine, n-Formyl-2-Mercapto- (9Ci)
CAS No.	57327-78-3
Molecular Formula	C4H7NO3S
Molecular Weight	149.17 g/mol
Synonyms	N-Formyl-2-mercaptoalanine; 2-Mercapto-N-formylalanine; (2R)-2-Amino-3-sulfanyl-N-formylpropanoic acid; N-Formylcysteine analog; Alanine derivative, N-formyl-2-mercapto-; NSC 163049; FMA
EINECS	Contact for details

Quality Control

Our Alanine, n-Formyl-2-Mercapto- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be sealed immediately after use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.