Description

Boc-γ-Abu-Oh CAS NO 57294-38-9 is a protected amino acid derivative, specifically the tert-butoxycarbonyl (Boc) derivative of γ-aminobutyric acid (GABA). This compound serves as a crucial key building block in solid-phase and solution-phase peptide synthesis, enabling the controlled elongation of peptide chains. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers for developing novel therapeutic peptides and bioactive compounds.

Application

• Peptide Synthesis Intermediate: A fundamental building block for the controlled incorporation of γ-aminobutyric acid (GABA) or its analogs into custom peptide sequences.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of novel peptide-based drug candidates targeting neurological and metabolic disorders.
• Bioconjugation: Serves as a linker or spacer molecule in the conjugation of peptides to other biomolecules, drugs, or surfaces for diagnostic and therapeutic applications.
• Neuroscience Research: Employed in the synthesis of GABA receptor ligands and probes to study neurotransmitter function and receptor interactions.
• Production of Protected Amino Acids: Acts as a precursor for further chemical modification to create other specialized, protected amino acid derivatives.

Basic Information

Product Name	Boc-γ-Abu-Oh
CAS No.	57294-38-9
Molecular Formula	C10H19NO4
Molecular Weight	217.26 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-4-aminobutyric acid; 4-[(2-Methylpropan-2-yl)oxycarbonylamino]butanoic acid; Boc-4-Abu-OH; Boc-GABA-OH; N-Boc-4-aminobutyric acid; γ-(Boc-amino)butyric acid; N-tert-Butoxycarbonyl-γ-aminobutyric acid; (4-{[(2-Methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid
EINECS	Contact for details

Quality Control

Our Boc-γ-Abu-Oh is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for peptide synthesis. Standard testing includes HPLC for assay and purity, chiral analysis, and residual solvent screening. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥98.5%
Optical Rotation	Contact for details
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.