Description

H-Ala-Ala-Pna is a specialized peptide derivative, specifically a dipeptide chromogenic substrate, widely recognized for its utility in biochemical research and enzyme activity studies. This compound is critical for researchers and manufacturers requiring precise tools for protease and peptidase analysis, offering high specificity and reliable performance. It is an essential reagent for pharmaceutical R&D, diagnostic kit development, and academic research in enzymology and proteomics.

Application

• Enzyme Substrate for Protease Assays: Primarily used as a chromogenic substrate for the kinetic study and quantification of various proteolytic enzymes, including elastase, subtilisin, and other serine proteases.
• Pharmaceutical Research & Development: Employed in high-throughput screening (HTS) platforms to identify and characterize novel enzyme inhibitors for therapeutic drug discovery.
• Diagnostic Reagent Manufacturing: Integrated into the formulation of diagnostic kits and reagents for clinical testing of enzymatic activity related to specific health conditions.
• Biochemical Mechanism Studies: Serves as a key tool in academic and industrial laboratories to investigate enzyme kinetics, substrate specificity, and catalytic mechanisms.
• Quality Control in Bioprocessing: Used to monitor and ensure the activity and purity of enzyme preparations used in industrial bioprocesses.

Basic Information

Product Name	H-Ala-Ala-Pna
CAS No.	57282-69-6
Molecular Formula	C16H22N4O4
Molecular Weight	334.37 g/mol
Synonyms	Ala-Ala-pNA; L-Alanyl-L-alanine 4-nitroanilide; N-(4-Nitrophenyl)-L-alanyl-L-alaninamide; H-Ala-Ala-pNA; Alanine Alanine p-Nitroanilide; AAPNA; AAPA; Substrate for Elastase
EINECS	Contact for details

Quality Control

Our H-Ala-Ala-Pna is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific research or GMP-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.