Description

H-Gly-Cys-Oh is a high-purity dipeptide building block, also known as Glycyl-L-cysteine, with the CAS registry number 57281-78-4. This compound is a critical intermediate for the synthesis of more complex peptides and for biochemical research, offering a versatile cysteine-containing fragment. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, proteomics, and as a precursor for glutathione synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, protein structure analysis, and metabolic pathway investigations.
• Antioxidant Precursor: An essential raw material in the synthesis of glutathione (γ-L-Glutamyl-L-cysteinylglycine), a vital cellular antioxidant.
• Cell Culture Media Supplement: Employed in specialized cell culture formulations to support cell growth and protein expression.
• Cosmetic Ingredient: Incorporated into advanced skincare formulations for its potential antioxidant and skin-conditioning properties.
• Chemical Biology Tool: Utilized in the development of affinity tags, bioconjugation probes, and other chemical tools due to the reactive thiol group of cysteine.

Basic Information

Item	Detail
Product Name	H-Gly-Cys-Oh
CAS No.	57281-78-4
Molecular Formula	C5H10N2O3S
Molecular Weight	178.21 g/mol
Synonyms	Glycyl-L-cysteine; Gly-Cys; L-Cysteinylglycine; Glycine-L-cysteine; N-Glycylcysteine; 2-[(2-Aminoacetyl)amino]-3-sulfanylpropanoic acid; H-Gly-Cys-OH; Gly-Cys-OH
EINECS	Contact for details

Quality Control

Our H-Gly-Cys-Oh is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis, and residual solvent screening to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	-80° to -90° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.