Description

n-[[4-(Dimethylamino)-1-Naphthalenyl]Methylene]-L-Phe-L-Phe-L-Phe-L-Phe-Ome is a specialized, high-purity tetrapeptide derivative featuring a dansyl-like fluorophore, making it a critical reagent for advanced biochemical research and development. This compound is engineered to provide exceptional sensitivity and specificity in fluorescence-based detection and labeling applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for developing novel assays, probes, and targeted therapeutic agents.

Application

• Fluorescent Probe Development: Serves as a key building block for creating sensitive fluorescent probes and sensors for enzymatic activity, protein-protein interactions, and cellular imaging.
• Peptide-Based Drug Discovery: Used in the synthesis and screening of novel peptide-drug conjugates (PDCs) and targeted therapeutics due to its integrated fluorophore and peptide backbone.
• Biochemical Assay Reagent: Acts as a substrate or tracer in fluorescence polarization (FP), fluorescence resonance energy transfer (FRET), and other high-throughput screening (HTS) assays.
• Diagnostic Kit Component: Incorporated into diagnostic kits and immunoassays for the detection of specific biomarkers with enhanced signal output.
• Academic & Industrial Research: A valuable tool for fundamental research in biochemistry, molecular biology, and chemical biology for studying peptide structure, function, and localization.
• Reference Standard: Employed as a certified reference material (CRM) or analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	n-[[4-(Dimethylamino)-1-Naphthalenyl]Methylene]-L-Phe-L-Phe-L-Phe-L-Phe-Ome
CAS No.	57237-95-3
Molecular Formula	C58H58N6O5
Molecular Weight	919.12 g/mol
Synonyms	Dansyl-Phe-Phe-Phe-Phe-OMe; N-[[4-(Dimethylamino)-1-naphthalenyl]methylene]-L-phenylalanyl-L-phenylalanyl-L-phenylalanyl-L-phenylalanine methyl ester; Tetraphenylalanine dansyl methyl ester; Fluorescent tetrapeptide derivative; Dns-Phe4-OMe; 4-Dimethylamino-1-naphthaldehyde-Phe-Phe-Phe-Phe-OMe Schiff base
EINECS	Contact for details

Quality Control

Our n-[[4-(Dimethylamino)-1-Naphthalenyl]Methylene]-L-Phe-L-Phe-L-Phe-L-Phe-Ome is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and performance. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.