Description

n-(1-Naphthalenylmethylene)-L-Val-L-Ile-L-Ala-Oet CAS NO 57237-92-0 is a synthetic, protected tripeptide derivative featuring a naphthalene-based protecting group. This compound is of significant value in advanced organic synthesis and pharmaceutical research, serving as a crucial key intermediate for the construction of complex peptide-based molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in proteomics and peptide chemistry research to study structure-activity relationships (SAR).
• Peptide Library Synthesis: A valuable component in solid-phase and solution-phase peptide synthesis for creating diverse compound libraries.
• Fine Chemical Synthesis: Intermediate for the production of specialized, high-value organic compounds with specific chiral configurations.
• Protecting Group Chemistry: The naphthalenylmethylene group serves as a protective moiety in multi-step synthetic pathways.
• Academic & Industrial R&D: Employed in laboratories for developing new synthetic methodologies and exploring new chemical entities.

Basic Information

Product Name	n-(1-Naphthalenylmethylene)-L-Val-L-Ile-L-Ala-Oet
CAS No.	57237-92-0
Molecular Formula	C30H39N3O4
Molecular Weight	505.65 g/mol
Synonyms	N-[(1-Naphthyl)methylidene]-L-valyl-L-isoleucyl-L-alanine ethyl ester; (S)-Ethyl 2-((S)-2-((S)-2-((1-Naphthylmethylene)amino)-3-methylbutanamido)-3-methylpentanamido)propanoate; L-Val-L-Ile-L-Ala-OEt Naphthalenylmethylene derivative; N-(1-Naphthalenylmethylene)valylisoleucylalanine ethyl ester; Protected Val-Ile-Ala tripeptide ester; Naphthaldehyde-protected VIA-OEt; N-1-Naphthylmethylidene-VIA-OEt; Naphthalen-1-ylmethylene protected tripeptide
EINECS	Contact for details

Quality Control

Our n-(1-Naphthalenylmethylene)-L-Val-L-Ile-L-Ala-Oet is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, IR, MS), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee (by Chiral HPLC)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.