Description

2'-Acetoxy-2,2,2-Trifluoroacetophenone is a specialized fluorinated aromatic ketone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the trifluoromethyl and acetoxy functional groups, enabling precise chemical transformations. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring the incorporation of a trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atoms contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique optical or surface properties.
• Liquid Crystal & OLED Materials: Acts as a fluorinated building block for electronic chemicals used in display and lighting technologies.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for Friedel-Crafts acylation and other reactions to introduce acetyl and fluorinated motifs.
• Fluorine Chemistry Studies: A valuable compound for investigating the effects of fluorine substitution on reaction mechanisms and physical properties.

Basic Information

Product Name	2'-Acetoxy-2,2,2-Trifluoroacetophenone
CAS No.	57230-51-0
Molecular Formula	C10H7F3O3
Molecular Weight	232.16 g/mol
Synonyms	1-[2-(Acetyloxy)phenyl]-2,2,2-trifluoroethanone; 2-Acetoxy-α,α,α-trifluoroacetophenone; 2-(Trifluoroacetyl)phenyl acetate; α,α,α-Trifluoro-2-acetoxyacetophenone; 2-Hydroxy-α,α,α-trifluoroacetophenone acetate; TFAA Acetate Derivative; 2-Acetoxybenzoyl trifluoride
EINECS	Contact for details

Quality Control

Our production of 2'-Acetoxy-2,2,2-Trifluoroacetophenone adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure high chemical purity and consistent lot-to-lot performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.