Description

Clorazepate Dipotassium Salt is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) primarily used in the synthesis of anxiolytic medications. Its significance lies in its role as a key precursor for producing controlled-release benzodiazepine formulations, ensuring consistent therapeutic efficacy. This compound is essential for manufacturers in the global pharmaceutical and fine chemical industries, particularly those developing and producing central nervous system (CNS) drugs.

Application

• Primary active pharmaceutical ingredient (API) in the manufacture of anxiolytic and sedative medications.
• Critical intermediate for the synthesis of benzodiazepine derivatives and related controlled-release pharmaceutical formulations.
• Used in research and development (R&D) for novel neuropharmacological compounds and drug delivery systems.
• Reference standard in analytical laboratories for quality control and regulatory compliance testing.
• Key starting material for producing generic versions of established benzodiazepine-based therapies.

Basic Information

Item	Details
Product Name	Clorazepate Dipotassium Salt
CAS No.	57109-90-7
Molecular Formula	C16H11ClK2N2O4
Molecular Weight	408.93 g/mol
Synonyms	Dipotassium Clorazepate; Clorazepate Dipotassium; Tranxene (as dipotassium salt); Azene; Dipotassium 7-Chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylate; Dipotassium 7-Chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylate; 3-Carboxy-7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one dipotassium salt
EINECS	Contact for details

Quality Control

Our Clorazepate Dipotassium Salt is manufactured under strict quality management systems, with purity levels typically meeting or exceeding 98.0% (HPLC). Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure compliance with ICH Q3A/B guidelines and relevant pharmacopeial standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.