Description

Boc-Leu-Met-Oh is a protected dipeptide derivative featuring leucine and methionine amino acid residues. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled elongation of peptide chains. It is primarily utilized by pharmaceutical researchers, biotech companies, and fine chemical manufacturers for the development of therapeutic peptides, biochemical probes, and advanced materials.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a building block in academic and industrial research for studying protein structure-function relationships.
• Peptide Library Construction: Essential component in combinatorial chemistry for generating diverse peptide libraries for drug discovery screening.
• API Development: Serves as an intermediate in the production of Active Pharmaceutical Ingredients (APIs) for various therapeutic areas.
• Custom Peptide Synthesis: Employed by CROs and CDMOs for the custom synthesis of specific peptide sequences for clients.

Basic Information

Product Name	Boc-Leu-Met-Oh
CAS No.	57092-20-3
Molecular Formula	C₁₆H₃₀N₂O₅S
Molecular Weight	362.48 g/mol
Synonyms	Boc-L-Methionyl-L-leucine; N-(tert-Butoxycarbonyl)-L-methionyl-L-leucine; Boc-Met-Leu-OH; (2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoyl]amino]-4-methylpentanoic acid; tert-Butoxycarbonylmethionylleucine; Boc-Met-Leu; N-Boc-L-methionyl-L-leucine; Boc-L-Met-L-Leu-OH
EINECS	Contact for details

Quality Control

Our Boc-Leu-Met-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	-20° to -25° (c=1, in DMF)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.