Description

2-Fluoro-1-Naphthol is a fluorinated naphthol derivative, a versatile building block prized for its unique electronic and steric properties introduced by the fluorine atom. This compound is essential for the synthesis of advanced materials and complex organic molecules, offering chemists a handle for fine-tuning reactivity and molecular interactions. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from ligand synthesis to the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediates: A key synthon in the synthesis of novel drug candidates, particularly in fluorinated APIs where the fluorine atom enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used as a precursor for developing advanced pesticides and herbicides, leveraging the fluorine substituent to improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Functional Material Precursor: Employed in the research and production of organic electronic materials, such as OLEDs and semiconductors.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized fluorinated dyes and pigments with unique color fastness and properties.
• Chemical Research & Development: A valuable reagent for academic and industrial research exploring new fluorination chemistry and reaction pathways.

Basic Information

Product Name	2-Fluoro-1-Naphthol
CAS No.	56874-95-4
Molecular Formula	C₁₀H₇FO
Molecular Weight	162.16 g/mol
Synonyms	2-Fluoronaphthalen-1-ol; 1-Naphthol, 2-fluoro-; 2-Fluoro-1-hydroxynaphthalene; 1-Hydroxy-2-fluoronaphthalene; 2-Fluoro-α-naphthol; NSC 406908; 2-Fluoronaphth-1-ol
EINECS	Contact for details

Quality Control

Our 2-Fluoro-1-Naphthol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and meets the stringent requirements of industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.