Description

H-Pro-His-Pro-Phe-His-Leu-Phe-Val-Tyr-Oh CAS NO 56842-71-8 is a synthetic nonapeptide sequence, also known as the C-terminal fragment of the peptide hormone Cholecystokinin (CCK). This compound is of significant value in biochemical and pharmacological research due to its role in studying receptor binding and signal transduction pathways. It is primarily utilized by research institutions and pharmaceutical development companies focused on neuroscience, gastrointestinal physiology, and peptide-based drug discovery.

Application

• Biochemical Research: Used as a reference standard and active fragment in studies of cholecystokinin receptor (CCK-R) interactions and function.
• Pharmacological Studies: Employed in vitro and in vivo to investigate the physiological effects of CCK, including satiety, anxiety, and pancreatic secretion.
• Drug Discovery: Serves as a key intermediate or lead compound in the development of novel therapeutics targeting the CCK pathway for metabolic and neurological disorders.
• Diagnostic Development: Potential use in the development of assay kits and diagnostic tools for measuring CCK levels or receptor activity.
• Academic Research: A critical tool for universities and research labs studying peptide hormones, neuropeptides, and their structure-activity relationships.

Basic Information

Product Name	H-Pro-His-Pro-Phe-His-Leu-Phe-Val-Tyr-Oh
CAS No.	56842-71-8
Molecular Formula	C58H74N14O10
Molecular Weight	1127.3 g/mol
Synonyms	CCK (27-35); Cholecystokinin Fragment 27-35; CCK-9; H-Pro-His-Pro-Phe-His-Leu-Phe-Val-Tyr-OH; CCK Nonapeptide; Sincalide fragment (27-35); Pro-His-Pro-Phe-His-Leu-Phe-Val-Tyr; CCK-27-35
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and analyzed under strict quality management systems. Each batch of H-Pro-His-Pro-Phe-His-Leu-Phe-Val-Tyr-Oh is subjected to comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, content, and analytical results are provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.