Description

N(1)-(4-Amino-2-Hydroxy-1-Oxobutyl)Sagamicin is a semi-synthetic derivative of the aminoglycoside antibiotic sagamicin, engineered for enhanced pharmacological properties. This compound is of significant interest for the development of novel antimicrobial agents, particularly against resistant bacterial strains. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of advanced antibiotic intermediates and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of next-generation aminoglycoside antibiotics.
• Antimicrobial Research: Used in biochemical and microbiological research to study structure-activity relationships (SAR) and mechanisms of action against bacteria.
• API Development: Serves as a critical building block in the development and scale-up of new Active Pharmaceutical Ingredients (APIs) with improved efficacy profiles.
• Veterinary Medicine: Potential application in the research and development of veterinary antibiotics for treating bacterial infections in animals.
• Reference Standard: Can be supplied as a high-purity analytical reference standard for quality control and regulatory testing in pharmaceutical laboratories.

Basic Information

Product Name	N(1)-(4-Amino-2-Hydroxy-1-Oxobutyl)Sagamicin
CAS No.	56824-15-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	6'-N-[(S)-4-Amino-2-hydroxybutyryl]gentamicin C1a; Sagamicin derivative; 6'-N-AHB-Gentamicin C1a; Antibiotic G-418 related compound; (S)-4-Amino-2-hydroxybutyryl-sagamicin; 1-N-[(S)-4-Amino-2-hydroxybutanoyl]sagamicin
EINECS	Contact for details

Quality Control

Our N(1)-(4-Amino-2-Hydroxy-1-Oxobutyl)Sagamicin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.