Description

5-Bromo-2,4-dimethoxypyrimidine is a versatile halogenated pyrimidine derivative, serving as a crucial building block in advanced organic synthesis. Its value lies in its functionalized aromatic ring, which provides reactive sites for cross-coupling and nucleophilic substitution reactions, enabling the construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of nucleoside analogs, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection chemicals.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions.
• Nucleophilic Aromatic Substitution: The methoxy and bromo groups allow for selective functionalization, enabling diverse chemical modifications.
• Chemical Biology & Proteomics: Used as a labeling reagent or building block for probes and inhibitors in biochemical research.

Basic Information

Product Name	5-Bromo-2,4-dimethoxypyrimidine
CAS No.	56686-16-9
Molecular Formula	C6H7BrN2O2
Molecular Weight	219.04 g/mol
Synonyms	5-Bromo-2,4-dimethoxypyrimidine; 2,4-Dimethoxy-5-bromopyrimidine; 5-Bromo-2,4-bis(methoxy)pyrimidine; 5-Bromopyrimidine-2,4-diol dimethyl ether; NSC 403914; 5-Bromo-2,4-pyrimidinediol, dimethyl ether
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,4-dimethoxypyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.