Description

Z-Asn-Gly-Oh is a protected dipeptide derivative, specifically N-benzyloxycarbonyl-L-asparaginylglycine. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), where its protecting groups allow for selective deprotection and controlled chain elongation. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers for the development of therapeutic peptides and complex biomolecules.

Application

• Pharmaceutical Intermediate: Key raw material in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or reagent in peptide chemistry studies and structure-activity relationship (SAR) investigations.
• Solid-Phase Peptide Synthesis (SPPS): An essential protected fragment for the controlled, sequential assembly of longer peptide chains.
• Combinatorial Chemistry: Building block for creating diverse peptide libraries for drug discovery and screening.
• Glycopeptide Synthesis: Potential precursor in the synthesis of glycopeptides, where the asparagine residue is a common glycosylation site.

Basic Information

Product Name	Z-Asn-Gly-Oh
CAS No.	56675-97-9
Molecular Formula	C₁₄H₁₇N₃O₆
Molecular Weight	323.30 g/mol
Synonyms	N-Cbz-L-Asparaginylglycine; Z-L-Asparaginylglycine; N-Benzyloxycarbonyl-L-asparaginylglycine; Cbz-Asn-Gly-OH; Z-Asn-Gly-OH; Nα-Carbobenzoxy-L-asparaginylglycine; (2S)-2-[[(2S)-4-Amino-2-(benzyloxycarbonylamino)-4-oxobutanoyl]amino]acetic acid; L-Asparagine, N2-[(phenylmethoxy)carbonyl]-, 1-glycyl-
EINECS	Contact for details

Quality Control

Our Z-Asn-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.