Description

Procalcitonin is a crucial peptide precursor of the hormone calcitonin, serving as a highly specific biomarker for severe systemic bacterial infections and sepsis. Its primary commercial and clinical value lies in its diagnostic application, where it enables rapid and accurate differentiation between bacterial and non-bacterial inflammation, guiding critical antibiotic therapy decisions. This product is essential for in-vitro diagnostic (IVD) kit manufacturers, clinical research organizations, and pharmaceutical R&D laboratories focused on developing and calibrating advanced diagnostic assays.

Application

• In-Vitro Diagnostic (IVD) Reagents: Core raw material for the production of immunoassay kits (e.g., ELISA, CLIA, LFIA) for the quantitative detection of procalcitonin in human serum or plasma.
• Biomarker Research: Critical standard and reference material for studies investigating sepsis, systemic inflammatory response syndrome (SIRS), and severe bacterial infections.
• Assay Calibration & Control: Used to prepare precise calibration curves and quality control samples to ensure the accuracy and reproducibility of diagnostic instruments.
• Antibody Production & Characterization: Serves as a key antigen for the generation and screening of high-affinity monoclonal and polyclonal antibodies specific to procalcitonin.
• Therapeutic Development: Research-grade material for investigating the role of procalcitonin in inflammatory pathways and potential therapeutic interventions.

Basic Information

Product Name	Procalcitonin
CAS No.	56645-65-9
Molecular Formula	C₁₄₈H₂₄₀N₄₄O₄₈S₂
Molecular Weight	Approx. 13,000 Da
Synonyms	Procalcitonin; PCT; Calcitonin Precursor; Preprocalcitonin; CALC-1; Pro-CT; Sepsis Marker Protein; Bacterial Infection Biomarker
EINECS	Contact for details

Quality Control

Our Procalcitonin is manufactured and tested under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, mass spectrometry for identity confirmation, and endotoxin testing. We provide full traceability and Certificates of Analysis (COA) detailing all specifications, ensuring the material meets the exacting requirements for diagnostic and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Endotoxin	< 1.0 EU/μg
Biological Activity	Assessed by immuno-reactivity

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.