Description

5-Amino-2-Chloropyrimidine is a high-value, halogenated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino group and a reactive chlorine atom, makes it an indispensable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other therapeutic agents targeting various diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for creating specialized polymers, ligands for catalysis, or organic electronic materials.
• Dye & Pigment Industry: Can be utilized in the synthesis of heterocyclic dyes and colorants.

Basic Information

Product Name	5-Amino-2-Chloropyrimidine
CAS No.	56621-90-0
Molecular Formula	C4H4ClN3
Molecular Weight	129.55 g/mol
Synonyms	2-Chloro-5-aminopyrimidine; 2-Chloro-5-pyrimidinamine; 5-Amino-2-chloropyrimidine; 5-Pyrimidinamine, 2-chloro-; 2-Chloropyrimidin-5-amine
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Chloropyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.