Description

Quinazoline, 2-Fluoro- (9Ci) is a fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmaceuticals and agrochemicals, where the fluorine atom can dramatically alter biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated quinazoline-based drug candidates, particularly kinase inhibitors and anticancer agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the fluorine moiety enhances bioactivity and environmental persistence.
• Material Science Precursor: Serves as a starting material for creating specialized fluorinated organic compounds used in electronic materials and liquid crystals.
• Chemical Biology Probe: Employed in medicinal chemistry to study structure-activity relationships (SAR) and for labeling applications.
• Academic & Contract Research: Essential for synthetic methodology development and exploratory research in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Quinazoline, 2-Fluoro- (9Ci)
CAS No.	56595-08-5
Molecular Formula	C8H5FN2
Molecular Weight	148.14 g/mol
Synonyms	2-Fluoroquinazoline; Quinazoline, 2-fluoro-; 2-Fluoro-1,3-diazanaphthalene; 2-Fluoro-benzo[d]pyrimidine; Fluorquinazoline; 2-F-Quinazoline; 56595-08-5; 2-Fluorquinazolin
EINECS	Contact for details

Quality Control

Our Quinazoline, 2-Fluoro- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.