Description

Hemoglobin Gower CAS NO 56592-05-3 is a specific embryonic hemoglobin variant, a critical protein complex in early human development. This high-purity biochemical is essential for research into hematopoiesis, oxygen transport mechanisms, and developmental biology. It is primarily utilized by research institutions, diagnostic manufacturers, and biotechnology companies focused on advanced life science studies and the development of specialized assays.

Application

• Biomedical Research: Fundamental studies on embryonic and fetal hemoglobin switching, gene expression, and developmental disorders.
• Diagnostic Reagent Development: Used as a standard or key component in the production of immunoassays and test kits for detecting specific hemoglobinopathies.
• Comparative Physiology Studies: Serves as a reference material for investigating oxygen-binding properties and evolutionary biology of respiratory proteins.
• Cell Culture & Differentiation Models: Employed in stem cell research to study and induce erythroid lineage differentiation in vitro.
• Biochemical Standard: Acts as a purified standard for chromatography (HPLC, CE) and spectrometry techniques in clinical and analytical laboratories.
• Pharmaceutical Target Investigation: Used in drug discovery research targeting hemoglobin-related diseases and conditions.

Basic Information

Product Name	Hemoglobin Gower
CAS No.	56592-05-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb Gower; Embryonic Hemoglobin; Hemoglobin ζ2ε2; Zeta2-Epsilon2 Tetramer; HbE; Gower-1 Hemoglobin; Hemoglobin Portland; Hb Portland-1; Early Embryonic Hemoglobin
EINECS	Contact for details

Quality Control

Our Hemoglobin Gower is produced and handled under stringent quality protocols suitable for research applications. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and biological activity. A detailed Certificate of Analysis (COA) documenting purity (by HPLC), spectral properties, and functional characteristics is provided with every shipment to guarantee traceability and consistency for your critical research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot into working volumes to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (UV-Vis)	Complies (Soret band ~414-415 nm)
Purity (HPLC)	≥ 95% (Main peak)
Protein Content (Biuret/BCA)	≥ 90%
Hemoglobin Type (Electrophoresis/CE)	Predominantly Hb Gower (ζ2ε2)
Solubility	Clear solution in appropriate buffer
Endotoxin	< 1.0 EU/mg (for cell culture grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.