Description

[β-Asp1]-Angiotensin II is a synthetic, biologically active peptide analog of the endogenous vasoconstrictor hormone Angiotensin II. This compound is of significant value for biochemical and pharmacological research, serving as a critical tool for studying the renin-angiotensin system (RAS), receptor binding, and cardiovascular physiology. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on hypertension, heart failure, and metabolic disorders.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of the renin-angiotensin-aldosterone system (RAAS) and its role in blood pressure regulation.
• Pharmacological Assays: Employed in in vitro and in vivo experiments to investigate Angiotensin II receptor (AT1/AT2) activity, signaling pathways, and antagonist screening.
• Diagnostic Development: Serves as a key antigen or calibrator in the development of immunoassays and test kits for measuring angiotensin-related biomarkers.
• Drug Discovery: A vital intermediate or pharmacological probe in the discovery and development of novel cardiovascular therapeutics and receptor modulators.
• Academic Studies: Utilized in university and institutional labs for teaching and advanced research into peptide hormone function and cardiovascular disease models.

Basic Information

Item	Details
Product Name	[β-Asp1]-Angiotensin II
CAS No.	56575-51-0
Molecular Formula	C₅₀H₇₁N₁₃O₁₂
Molecular Weight	1030.2 g/mol
Synonyms	Asp(1)-Angiotensin II; [Asp1]-Angiotensin II; β-Aspartyl1-angiotensin II; Angiotensin II, 1-β-aspartic acid; DRVYIHPF; H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH (β-Asp1 isomer); [β-Asp1]AII
EINECS	Contact for details

Quality Control

Our [β-Asp1]-Angiotensin II is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications. Stability and sterility testing are available for specific application requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.