Description

H-Nva-Ome HCl is a protected amino acid derivative, specifically the methyl ester hydrochloride salt of Norvaline. This compound serves as a crucial building block in organic synthesis and peptide chemistry, offering a protected side chain for controlled reactions. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in the development of novel peptides, bioactive molecules, and complex organic intermediates.

Application

• Peptide Synthesis: As a key intermediate for incorporating the non-proteinogenic amino acid Norvaline into peptide chains.
• Pharmaceutical Research: Used in the R&D of new drug candidates, enzyme inhibitors, and metabolic probes.
• Bioconjugation: Serves as a linker or spacer molecule in the preparation of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology: Employed in the study of protein structure-function relationships and the design of peptide mimetics.
• Fine Chemical Production: Acts as a precursor for the synthesis of more complex, high-value specialty chemicals.
• Academic Research: Utilized in university and institutional labs for synthetic chemistry and biochemistry projects.

Basic Information

Product Name	H-Nva-Ome HCl
CAS No.	56558-30-6
Molecular Formula	C6H14ClNO2
Molecular Weight	167.63 g/mol
Synonyms	L-Norvaline methyl ester hydrochloride; Norvaline methyl ester HCl; H-Norval-OMe·HCl; Methyl L-2-aminopentanoate hydrochloride; (S)-2-Aminopentanoic acid methyl ester hydrochloride; 2-Aminopentanoic acid methyl ester hydrochloride; Methyl norvalinate hydrochloride
EINECS	Contact for details

Quality Control

Our H-Nva-Ome HCl is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric integrity. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]20/D: Specific range available
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.