Description

4-(Trifluoromethylthio)Benzyl Alcohol is a versatile fluorinated aromatic building block characterized by the presence of both a benzyl alcohol group and a trifluoromethylthio (SCF₃) moiety. This unique structure makes it a valuable intermediate for synthesizing advanced molecules with enhanced properties like metabolic stability and lipophilicity. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the SCF₃ group can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated as a functional monomer to impart specific properties like chemical resistance or altered surface energy into specialty polymers.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create novel ligands and catalysts for asymmetric synthesis and cross-coupling reactions.
• Advanced Material Research: Acts as a building block in materials science for developing sensors, coatings, and other functional materials with tailored properties.

Basic Information

Product Name	4-(Trifluoromethylthio)Benzyl Alcohol
CAS No.	56456-52-1
Molecular Formula	C₈H₇F₃OS
Molecular Weight	208.20 g/mol
Synonyms	α-(Trifluoromethylthio)-p-tolyl alcohol; (4-(Trifluoromethylthio)phenyl)methanol; 4-(Trifluoromethylsulfanyl)benzyl alcohol; p-(Trifluoromethylthio)benzyl alcohol; 4-SCF3-Benzyl alcohol; Benzyl alcohol, 4-[(trifluoromethyl)thio]-; 1-[4-(Trifluoromethylthio)phenyl]methanol
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethylthio)Benzyl Alcohol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing all critical specifications. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.