Description

Angiotensin III, Ile(8)- is a bioactive peptide fragment derived from the renin-angiotensin system. This compound is of significant interest for its role in cardiovascular research and as a critical reference standard in analytical and diagnostic applications. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of in-vitro diagnostic kits.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the renin-angiotensin system, blood pressure regulation, and cardiovascular physiology.
• Pharmaceutical Development: Serves as a key intermediate or reference material in the discovery and development of novel cardiovascular and renal therapeutics.
• Diagnostic Manufacturing: Employed as a critical calibrant and quality control component in the production of immunoassay kits for hormone and peptide analysis.
• Biochemical Assays: Acts as a substrate or ligand in enzymatic activity studies and receptor binding assays to elucidate biological pathways.
• Academic & Clinical Studies: Provides a pure, well-characterized compound for experimental protocols in university and hospital research laboratories.

Basic Information

Product Name	Angiotensin III, Ile(8)-
CAS No.	56451-37-7
Molecular Formula	C46H68N12O10
Molecular Weight	931.1 g/mol
Synonyms	Ile8-Angiotensin III; Angiotensin (5-8) tetrapeptide; Arg-Val-Tyr-Ile-His-Pro-Phe; [Ile8]-Angiotensin III; Des-Asp1-Ile8-Angiotensin II; AIII (Ile8); Angiotensin III (Ile8) fragment; H-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
EINECS	Contact for details

Quality Control

Our Angiotensin III, Ile(8)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.