Description

Netilmicin Sulfate is a semi-synthetic aminoglycoside antibiotic derived from sisomicin. This compound is valued for its broad-spectrum bactericidal activity, particularly against Gram-negative bacteria, and its relative resistance to certain bacterial enzymes that inactivate other aminoglycosides. It is a critical active pharmaceutical ingredient (API) primarily required by pharmaceutical manufacturers for the formulation of injectable antibiotic solutions.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable formulations for the treatment of serious systemic infections.
• Ophthalmic Solutions: Used in the manufacture of eye drops and ointments for treating bacterial conjunctivitis and other ocular infections.
• Veterinary Medicine: Employed in veterinary pharmaceuticals for treating bacterial infections in livestock and companion animals.
• Research & Development: Serves as a reference standard and biochemical tool in microbiological and pharmacological research.
• Hospital Compounding: Utilized in hospital pharmacy settings for preparing specialized dosage forms when required.

Basic Information

Product Name	Netilmicin Sulfate
CAS No.	56391-57-2
Molecular Formula	C21H41N5O7 • xH2SO4
Molecular Weight	Netilmicin base: 475.59 g/mol (as free base)
Synonyms	1-N-Ethylsisomicin Sulfate; Sch 20569 Sulfate; Netromycin; Netilmicin Sulphate; Certomycin; Netillin; Netilmicin (base); Ethylsisomicin Sulfate
EINECS	Contact for details

Quality Control

Our Netilmicin Sulfate is manufactured and tested under strict quality management systems. It is produced to meet the exacting standards required for pharmaceutical active ingredients, with testing protocols aligned with major pharmacopoeias. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing purity, potency, and impurity profiles to ensure regulatory compliance and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms
Identification (HPLC)	Retention time corresponds to reference standard
Assay (on dried basis)	95.0% - 102.0%
pH (1% solution)	3.5 - 5.5
Loss on Drying	≤ 8.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%
Bacterial Endotoxins	< 1.0 EU/mg (as per intended use)
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.