Description

Netilmicin is a semi-synthetic aminoglycoside antibiotic derived from sisomicin. This product is valued for its broad-spectrum bactericidal activity, particularly against Gram-negative bacteria, and its relative resistance to certain bacterial enzymes that inactivate other aminoglycosides. It is a critical active pharmaceutical ingredient (API) required by pharmaceutical manufacturers for the formulation of injectable antibiotic solutions. Netilmicin CAS NO 56391-56-1 is supplied to meet the stringent demands of the global pharmaceutical industry.

Application

Netilmicin is primarily utilized as an active pharmaceutical ingredient in the production of sterile injectable formulations. Its key applications include:

• Pharmaceutical API: Core ingredient in the manufacture of injectable antibiotic drugs.
• Treatment of Serious Infections: Used in formulations targeting severe bacterial infections, including septicemia, complicated urinary tract infections, and intra-abdominal infections.
• Hospital-use Pharmaceuticals: Essential for producing parenteral medications administered in clinical settings for patients with compromised immune systems or life-threatening conditions.
• Research & Development: Serves as a reference standard and raw material in pharmaceutical R&D for developing new therapeutic formulations and conducting microbiological studies.

Basic Information

Product Name	Netilmicin
CAS No.	56391-56-1
Molecular Formula	C21H41N5O7
Molecular Weight	475.59 g/mol
Synonyms	Netilmicin Sulfate; 1-N-Ethylsisomicin; Sch 20569; Certomycin; Netromycin; Netilmicin A; (2S,3R,4S,5S,6R)-4-Amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(ethylamino)-5-methyl-3,4,5,6-tetrahydro-2H-pyran-3,5-diol
EINECS	260-155-8

Quality Control

Our Netilmicin is produced and tested under strict quality management systems to ensure it meets the highest standards for pharmaceutical use. Quality assurance protocols are designed to comply with current Good Manufacturing Practices (cGMP). Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and impurity profiles, ensuring traceability and batch-to-batch consistency for our global clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 10.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 1.0 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.