Description

n-Phosphorylleucyltryptophan is a synthetic phosphorylated dipeptide derivative, specifically the phosphoric acid ester of leucyl-tryptophan. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a potential precursor or model compound for studying enzyme kinetics, signal transduction pathways, and peptide-based drug design. It is primarily utilized by research institutions, pharmaceutical R&D departments, and specialty chemical manufacturers focused on advanced peptide chemistry and proteomics.

Application

• Biochemical Research: Serves as a key intermediate or reference standard in studies of kinase and phosphatase activity, phosphopeptide metabolism, and intracellular signaling cascades.
• Pharmaceutical Development: Used as a building block or precursor in the synthesis of more complex phosphopeptides with potential therapeutic applications.
• Proteomics & Mass Spectrometry: Acts as a calibration standard or model compound for developing and validating analytical methods for phosphopeptide detection and quantification.
• Enzyme Substrate Studies: Employed as a synthetic substrate to investigate the specificity and catalytic mechanisms of proteolytic enzymes and phosphotransferases.
• Academic Research: Utilized in university and institutional labs for fundamental research in bioorganic chemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	n-Phosphorylleucyltryptophan
CAS No.	56361-75-2
Molecular Formula	C17H24N3O6P
Molecular Weight	397.36 g/mol
Synonyms	Leucylphosphotryptophan; L-Leucyl-L-tryptophan phosphoric acid ester; Phospholeucyltryptophan; H-Leu-Trp-OH phosphate; O-Phosphoryl-Leu-Trp; N-Phosphoryl-Leu-Trp dipeptide; Phosphorylated Leu-Trp; 56361-75-2
EINECS	Contact for details

Quality Control

Our n-Phosphorylleucyltryptophan is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis and purification to meet specific project requirements are available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.