Description

4-Cyclohexyl-Benzenesulfonyl Chloride CAS NO 56354-57-5 is a versatile and reactive organosulfur compound primarily used as a key sulfonylation reagent and synthetic intermediate in advanced organic synthesis. Its molecular structure, featuring a cyclohexyl group attached to a benzenesulfonyl chloride core, makes it valuable for introducing the 4-cyclohexylphenylsulfonyl moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who require high-purity building blocks for drug discovery and the development of active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly for introducing sulfonamide groups which are prevalent in many therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the sulfonyl chloride group acts as a reactive handle for further derivatization.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and advanced materials that require specific sulfonated aromatic components.
• Chemical Biology & Proteomics: Acts as a reagent for modifying proteins, peptides, or other biomolecules to study function or create biochemical probes.
• Dye and Pigment Manufacturing: Functions as an intermediate in the synthesis of specialized sulfonated dyes and colorants.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed coupling reactions (e.g., Suzuki, Stille) to create complex biaryl systems after appropriate functional group transformation.

Basic Information

Product Name	4-Cyclohexyl-Benzenesulfonyl Chloride
CAS No.	56354-57-5
Molecular Formula	C12H15ClO2S
Molecular Weight	258.76 g/mol
Synonyms	p-Cyclohexylbenzenesulfonyl chloride; 4-Cyclohexylphenylsulfonyl chloride; (4-Cyclohexylphenyl)sulfonyl chloride; Benzenesulfonyl chloride, 4-cyclohexyl-; 1-Cyclohexyl-4-(chlorosulfonyl)benzene; 4-Cyclohexylbenzene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Cyclohexyl-Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.