Description

(Des-Asp1)-Angiotensin I is a specific, biologically active peptide fragment derived from the renin-angiotensin system, serving as a crucial intermediate in the study of cardiovascular regulation and hypertension. This compound is valued for its high purity and specificity, making it an essential tool for biochemical research and pharmaceutical development. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in cardiovascular disease research, enzyme kinetics studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a precise substrate or standard in enzymatic assays to study the activity of Angiotensin Converting Enzyme (ACE) and other related proteases.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the research and development of antihypertensive drugs and cardiovascular therapies.
• Diagnostic Reagents: Employed in the formulation of calibration standards and controls for clinical diagnostic kits measuring components of the renin-angiotensin system.
• Metabolic Pathway Studies: Facilitates research into the metabolic pathways of angiotensin peptides and their role in blood pressure regulation and fluid balance.
• Academic Research: A critical reagent for university and institutional labs investigating cardiovascular physiology, peptide hormone action, and signal transduction mechanisms.
• Quality Control: Acts as a reference material for the quality assurance and purity verification of related peptide pharmaceuticals and research chemicals.

Basic Information

Item	Detail
Product Name	(Des-Asp1)-Angiotensin I
CAS No.	56317-01-2
Molecular Formula	C₄₈H₇₀N₁₂O₁₂
Molecular Weight	1007.15 g/mol
Synonyms	Angiotensin I (1-9); [Des-Asp1]-Angiotensin I; Angiotensin I (2-10); Angiotensin I Fragment 2-10; DRVYIHPFHL; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu (2-10); H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH
EINECS	Contact for details

Quality Control

Our (Des-Asp1)-Angiotensin I is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.