Description

4-Chloro-6-Methyl-2-[3-(Trifluoromethyl)Phenyl]Pyrimidine is a high-value pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its molecular architecture, featuring a chloro-methyl-pyrimidine core and a trifluoromethylphenyl substituent, makes it indispensable for creating compounds with tailored electronic and steric properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory therapies.
• Agrochemical Synthesis: Serves as a critical precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrimidine scaffold.
• Material Science Research: Used in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Employed in creating specialized molecular probes and inhibitors for studying enzyme function and signal transduction pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	4-Chloro-6-Methyl-2-[3-(Trifluoromethyl)Phenyl]Pyrimidine
CAS No.	56302-42-2
Molecular Formula	C12H8ClF3N2
Molecular Weight	272.65 g/mol
Synonyms	2-(3-(Trifluoromethyl)phenyl)-4-chloro-6-methylpyrimidine; 4-Chloro-6-methyl-2-(3-trifluoromethylphenyl)pyrimidine; 4-Chloro-2-(3-(trifluoromethyl)phenyl)-6-methylpyrimidine; 4-Chloro-6-methyl-2-(α,α,α-trifluoro-m-tolyl)pyrimidine; 2-(3-Trifluoromethylphenyl)-4-chloro-6-methylpyrimidine
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-6-Methyl-2-[3-(Trifluoromethyl)Phenyl]Pyrimidine is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.