Description

2-(Fluoromethyl)-6-Nitro-3-o-Tolylquinazolin-4(3H)-One is a specialized fluorinated quinazolinone derivative, a high-value synthetic intermediate prized for its unique molecular scaffold. This compound matters for its role in facilitating complex chemical transformations, particularly in the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of the quinazolinone core.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study biological processes and protein functions.
• Material Science: Investigated for incorporation into advanced organic materials, such as organic semiconductors or liquid crystals, due to its fused aromatic structure.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological studies and novel synthetic route exploration.

Basic Information

Product Name	2-(Fluoromethyl)-6-Nitro-3-o-Tolylquinazolin-4(3H)-One
CAS No.	56287-73-1
Molecular Formula	C₁₆H₁₂FN₃O₃
Molecular Weight	313.29 g/mol
Synonyms	2-(Fluoromethyl)-6-nitro-3-(2-methylphenyl)-3,4-dihydroquinazolin-4-one; 3-(2-Methylphenyl)-2-(fluoromethyl)-6-nitro-4(3H)-quinazolinone; 6-Nitro-3-o-tolyl-2-(fluoromethyl)quinazolin-4(3H)-one; 4(3H)-Quinazolinone, 2-(fluoromethyl)-6-nitro-3-(2-methylphenyl)-; 2-(Fluoromethyl)-6-nitro-3-(o-tolyl)quinazolin-4(3H)-one; 56287-73-1; 3-(2-Methylphenyl)-2-(fluoromethyl)-6-nitroquinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 2-(Fluoromethyl)-6-Nitro-3-o-Tolylquinazolin-4(3H)-One is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure high consistency and reliability for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.