Description

Nα-Acetylglutamine Methyl Ester is a protected derivative of the amino acid glutamine, specifically designed for advanced peptide synthesis and biochemical research. This compound is valued for its role as a key building block in the production of complex peptides and active pharmaceutical ingredients (APIs), offering enhanced stability and controlled reactivity. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers focused on peptide-based therapeutics and high-value specialty chemicals.

Application

• Peptide Synthesis: A crucial protected intermediate for the solid-phase and solution-phase synthesis of complex peptides and proteins.
• Pharmaceutical Research: Used in the development and scale-up of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Biochemical Studies: Serves as a reagent in enzymatic studies and metabolic pathway research involving glutamine derivatives.
• Fine Chemical Production: Acts as a specialized building block for creating custom amino acid derivatives and other high-value organic compounds.

Basic Information

Product Name	Nα-Acetylglutamine Methyl Ester
CAS No.	56159-64-9
Molecular Formula	C8H14N2O4
Molecular Weight	202.21 g/mol
Synonyms	Ac-Gln-OMe; N-Acetyl-L-glutamine methyl ester; L-Glutamine, N-acetyl-, methyl ester; Methyl N-acetyl-L-glutaminate; Nα-Acetyl-L-glutamine methyl ester; N-Acetylglutamine methyl ester; (S)-Methyl 2-acetamido-4-carbamoylbutanoate
EINECS	Contact for details

Quality Control

Our Nα-Acetylglutamine Methyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Quality is verified through comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range available
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.